About US - Management - Shim, Jae Chul

Dr. Shim is an experienced organic chemist in multistep chemical synthesis in medicinal/process research with a Ph.D. from University of California, Irvine and postdoctoral research experience at Harvard University.

His Ph.D. thesis detailed the first total synthesis of Amaryllidaceae alkaloids. His enthusiasm in organic chemistry started with B.S. and M.S. at Seoul National University and the title of his master thesis was “A F-19 NMR study on the charge-delocalizing ability of the geometrically constrained cyclopropylcarbinyl cationic systems”.

 
He has been working with major pharmaceutical companies, such as Pfizer and Biogen as a Senior Scientist in medicinal chemistry, contributing to the development of new therapeutics in various diseases including cancer and inflammation.

One of his recent achievements in research project was in the area of Inflammation/Immunology, Oncology and Infectious Diseases. During his professional tenure, he published many different scientific journals. Most recent topics include “Synthesis and PKC Inhibitory Activity of a Series of 5-Vinyl Phenyl Sulfonamide-3-Pyridinecarbonitriles” and “First Generation of 5-Vinyl-3-Pyridinecarbonitrile PKC Inhibitors”.

Mr. Shim is also a major contributor for the numerous US patents in following:

“Preparation of 9-Aminocarbonyl Substituted Derivatives of Glycylcyclines as Antibiotics”
“Preparation of 3,3-dialkyl-2,3-dihydro-4-chromanones by alkylation of 2,3-dihydro-4- chromanones at low temperatures”
“Method of Forming Amino Acid-Derived Diaminopropanols Useful as Chemical Intermediates for Protease Inhibitors”
“Method Forming Protease Inhibitor Synthetic Intermediates”
“Amino Acid-Derived Diaminopropanols”
“Method Forming Amino Acid-Derived Diaminopropanols”

Currently, Mr. Shim is a member of the American Chemical Society (ACS), Korean-American Scientists and Engineers Association (KSEA) and Korean-American Society of Biotech and Pharmaceuticals (KASBP).